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Because of the variety of triggers, it can be a challenging condition to treat.
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Therapy with results in a significant delay in the time until first exacerbation, and fewer exacerbations per year, than treatment with salmeterol ().
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Tiotropium can improve lung function, reduce symptoms and exacerbations, and improve quality of life with once-daily dosing ().
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You should read all product information carefully before purchasing and if you suspect you have a medical problem, promptly consult your health-care professional.
Spiriva does not treat sudden episodes of breathing problems (bronchospasm).
The FDA is urging caution for patients using Spiriva and suggesting they speak with their physician about determining their best course of action.
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As a LAMA, it is steroid-free and works differently than a long-acting beta 2 agonist (LABA).
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Emphysema is one of the diseases classified as COPD.
The drug opens up the narrow air passages, which allow oxygen to reach lungs and hence is used as a long term medication.
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Repeat steps 1 and 2 so that you get the full dose.
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Read your prescription label or the patient information guide from your healthcare provider or pharmacist before initiating treatment.
Erythromycin had a similar effect in another trial, but has poor gastrointestinal tolerability.
These drugs include tiotropium (Spiriva), ipratropium bromide (brand name Atrovent) or Combivent, which is ipratropium combined with albuterol.
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Trough FEV 1 increased after 1 week of daily administration and remained consistently greater than that for placebo through the treatment period.
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In our study, the decline in lung function averaged 30 ml per year before bronchodilation and 41 ml per year after bronchodilation in the two study groups, a change that is less than that in any of the previous studies.
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FDA informed healthcare professionals that FDA has reviewed preliminary data from UPLIFT (Understanding the Potential Long-Term Impacts on Function with Tiotropium), a large, 4-year, placebo controlled clinical trial with Spiriva HandiHaler in approximately 6000 patients with chronic obstructive pulmonary disease.
COPD is mainly caused by smoking or inhaling dust, which leads to blockage or narrowing of the airways.
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Improvement of lung function was maintained for 24 hours after a single dose and consistently maintained over the 1-year treatment period with no evidence of tolerance.
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It is important that you learn exactly how to use your inhaler.
By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart.
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The Catechism does not take up this line of reason in response to drugs, but rather demonstrates more clearly how drugs violate the commands of God, specifically the Fifth Commandment.
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Tiotropium also improved lung function, as compared with placebo, beyond the improvement resulting from serial administration of maximal doses of salbutamol and ipratropium.
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Adequate justification for dose selection will be provided.
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We all get the occasional call from a patient who has just read the package insert for a specific medication and is worried about the precaution that the particular drug might not be safe for individuals with a known history of glaucoma.
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To diagnose asthma, a health care professional will usually take a full health history, including family medical history, and inquire about the presence of any symptoms that appear to be asthma-related and what might be triggering those symptoms (allergies, pets, smoke in the home, foods, etc.
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Leukotriene antagonists include montelukast (Singulair, generic), zafirlukast (Accolate, generic), and zileuton (Zyflo).
Patients with COPD can learn to perform a variety of self-help measures that may help improve their symptoms and their ability to participate in everyday activities.
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Other diseases that must be considered during diagnosis are pneumonia, bronchitis, severe allergic reactions, pulmonary embolism, cancer, heart failure, tumors, psychosomatic illnesses, and certain rare disorders.
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